Abalone Bio
Abalone Bio, based in Emeryville, CA, specializes in discovering antibody drugs for cell surface receptors and has developed treatments for pain and inflammatory diseases.
Company Overview
Abalone Bio, located in Emeryville, CA, operates in the healthcare industry with a focus on drug discovery and delivery. The company is part of the Y-Combinator W20 batch and employs a small team of 12 dedicated professionals. The company is well-regarded for its innovative technology that identifies antibody drugs capable of modulating cell surface receptors. Abalone Bio’s mission extends to discovering treatments for various conditions, such as neuropathic pain, inflammatory, and fibrotic diseases.
Technological Innovations
Abalone Bio has developed groundbreaking technology aimed at finding antibody drugs that activate and modulate cell surface receptors. Their platform achieves this through a combination of engineered living cells and data-driven computation. This technology is compatible with VHH, scFvs, and Fabs, allowing for the activation of both small and large molecule receptors. Additionally, the platform is capable of discovering allosteric modulators and antagonists, contributing to its versatile application in drug discovery.
Key Discoveries
Among its notable achievements, Abalone Bio discovered a novel antibody that activates a non-opioid receptor known for producing analgesia. This significant discovery is in development as a potential treatment for neuropathic pain and holds promise for inflammatory and fibrotic diseases. These key discoveries are a testament to the company’s innovative approach toward addressing complex medical challenges.
Funding and Support
Abalone Bio has secured substantial backing through grants and investments from reputed organizations, including the National Science Foundation (NSF), National Institutes of Health (NIH), YCombinator, Pioneer Fund, Harmonix Fund, BoxOne Ventures, MetaPlanet, FMG Ventures, and Gravity Fund. This robust support reflects confidence in the company’s technological capabilities and its potential to deliver impactful healthcare solutions.
Careers at Abalone Bio
Abalone Bio offers career opportunities for individuals interested in advancing healthcare technology. Current open positions include Research Associate 2 and Sr. Research Associate. These roles provide an opportunity to work within a dynamic, partly remote team and contribute to the development of innovative therapies. The company seeks passionate and talented professionals eager to make a meaningful impact in drug discovery.
